Therapeutic Efficacy of Nanocomplex of Poly(Ethylene Glycol) and Catechin for Dry Eye Disease in a Mouse Model.

Self-assembled micellar nanocomplexes comprising green tea catechin derivatives and protein drugs for cancer therapy

When designing drug carriers, the drug-to-carrier ratio is an important consideration, because the use of high quantities of carriers can result in toxicity as a consequence of poor metabolism and elimination of the carriers. However, these issues would be of less concern if both the drug and carrier had therapeutic effects. (-)-Epigallocatechin-3-O-gallate (EGCG), a major ingredient of green t...

Study of Surface Tension of Binary Mixtures of Poly (Ethylene Glycol) in Water and Poly (Propylene Glycol) in Ethanol and its Modeling Using Neural Network

Effect of Ethylene Oxide Functional Groups in PEBA-CNT Membranes on CO2/CH4 Mixed Gas Separation

Poly (ether-block-amide) /poly (ethylene glycol)/ carbon nanotubes mixed matrix membranes have been successfully fabricated using solvent evaporation method to determine the effect of ethylene oxide groups on the performance of produced membranes. The effects of CNTs (2-8 wt%) and PEG (up to 50 wt%)were investigated in both single and mixed gas test setup in different temperature and pressure. ...

Translational Antidote Research: A Bedside to Bench Tale

Although antidote development should proceed in an orderly fashion from observation, to experimental and safety studies, to clinical trials, this sequence is not always precisely followed. The development of fomepizole as an antidote for toxic alcohol and glycol poisoning is an example of how this may not be the case. Interest in the development of fomepizole was spurred in the 1960s. Shortly t...

Electrocatalytic Oxidation of Ethanol and Ethylene Glycol onto Poly (o-Anisidine)-Nickel Composite Electrode

In this work, poly (o-Anisidine) (POA) was prepared by consecutive potential cycling in an acidic monomer solution at the surface of Carbon Paste Electrode (CPE). Nickel ions were dispersed into the polymer by immersing the electrode in NiSO4 solution. The prepared Ni/POA/CPE was characterized by scanning electron microscopy, energy dispersive X-ray spectroscopy, Atomic Force Mic...